Raw material of HPMC capsule shell
Purified water: refers to bottled water produced by distillation, deionization, reverse osmosis and other methods, which conforms to the definition of purified water in the latest edition of the US Pharmacopoeia.
HPMC: is an important non-ionic cellulose mixed ether. Odorless, tasteless, non-toxic, the finished product is white powder or loose fibrous, and the particle size is sieved through 80 meshes. It does not react with heavy metals. HPMC is actually a methyl cellulose modified methane oxide (methyl oxypropylene ring), so it has similar characteristics to methyl cellulose soluble in cold water, insoluble in hot water, and its solubility in organic solvents is higher than that of water soluble Good, soluble in anhydrous methanol, ethanol, also soluble in chlorinated hydrocarbons such as dichloromethane, trichloromethane and trimethoxy. Soluble in anhydrous methanol and ethanol, chlorinated hydrocarbons (such as dichloromethane, trichloroethane) and acetone, isopropanol, diacetone alcohol and other organic solvents.
Gelling agent: Gelling agent refers to the preparation of latex thick liquid or semi-solid preparation of homogeneous, suspension or emulsion type of drugs and appropriate excipients. The gelling agent has a single-phase dispersion system and a two-phase dispersion system. It is a gelling agent of a two-phase dispersion system. The colloidal particles of small molecular inorganic drugs have a network structure in the liquid and have thixotropy, also known as mixed suspension condensation. Glue, such as aluminum hydroxide gel. Gels for topical application are monodisperse systems and are divided into hydrogels and oil-based gels.