Enteric Gelatin Hollow Capsules

Update:04-05-2018
Summary:

Gelatin hollow capsules are hollow hard capsules made f […]

Gelatin hollow capsules are hollow hard capsules made from capsules made of gelatin and excipients, which are easy to disintegrate and release in gastric juice. Compared with tablets and pills, the capsules have higher bioavailability.

    Enteric-coated gelatin hollow capsules are hollow hard gelatin capsules made of gelatin plus excipients and suitable enteric materials, which are divided into enteric capsules and colon enteric capsules. Enteric-coated capsules are targeted capsule preparations that do not disintegrate in gastric juices and disintegrate in intestinal fluids; and enteric-coated capsules are not disintegrable in gastric juice and intestinal fluid, and are disintegrated in colonic fluids. Place targeted capsule products. According to the "Chinese Pharmacopoeia" (2015 Edition • Part IV) standard, in addition to the disintegration time limit, enteric-coated capsules for tightness, sulfites, parabens, chlorohydrin, ethylene oxide, loss on drying, flaming Residues of residue, chromium, heavy metals and microbiological tests were in complete agreement with gelatin hollow capsules.

    Plant hollow capsules mainly include hollow capsules mainly composed of hydroxypropylmethyl cellulose (HPMC) and pullulan. The plant hollow capsule solves the problems of easy brittleness and cross-linking curing reaction of the traditional Chinese medicine capsule preparation, wherein the hydroxypropyl methyl cellulose hollow capsule solves the brittleness problem of the traditional Chinese medicine capsule preparation, and is suitable for Chinese medicines or health care products with strong hygroscopicity. Filled with foods, hydroxypropyl starch hollow capsules are hollow hard capsules made from hydroxypropyl starch plus excipients. The Chinese Pharmacopoeia (2015 edition, Part IV) regulates the tightness, friability, disintegration time limit, loss on drying, ignition residue, heavy metals, and microbiological limit check items. Due to the different nature of the raw material for the coating, it is hollow with gelatin. Compared with capsules and enteric-coated gelatin hollow capsules, the inspection requirements for the disintegration time limit and loss on drying weight were slightly reduced.

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