Vegetable hollow capsules VS gelatin hollow capsules

Update:11-10-2021
1. Plant hollow capsules are an industry that does not pollute the environment
As we all know, the production and extraction of animal gelatin is made from animal skin and bone as raw materials and fermented through chemical reactions. A large number of chemical components are added in the process. Anyone who has been to the gelatin factory knows that a lot of peculiar smell is emitted during the production process, and a lot of water resources are used, which causes serious pollution to the air and water environment.
In western developed countries, many gelatin manufacturers have moved their factories to third world countries due to national regulations to reduce pollution to their own environment. Many plant gums are extracted by physical extraction methods, which are extracted from marine and terrestrial plants, and will not produce rotten foul odors. It also greatly reduces the amount of water used and reduces environmental pollution. In the production process of capsules, no harmful substances are added, and there is absolutely no environmental pollution. Gelatin's waste recycling rate is low, and a large number of pollution sources are generated when the waste is disposed of. Therefore, our plant capsule production company can be called a "zero emission" company.
2. Stability of raw materials for plant hollow capsules
The raw materials for the production of gelatin come from different animal carcasses such as pigs, cattle, and sheep. In recent years, the popular mad cow disease, avian influenza, blue ear disease, foot-and-mouth disease, etc., are all derived from animals. When a traceability investigation of a drug is required, it is often difficult to trace when the raw materials of the capsule are taken into consideration. The vegetable gum is derived from natural plants, which can better solve the above problems.
The US FDA issued guidelines earlier, hoping that in recent years, the market share of hollow vegetable capsules in the US market will reach 80%. One of the main reasons is the above-mentioned problem.
Nowadays, many pharmaceutical companies are repeatedly lowering prices for hollow capsule suppliers because of cost issues. In order to gain a foothold in the difficult living environment, hollow capsules can only use cheap gelatin with ignorance of their conscience.
According to a survey by the China Gelatin Association, the current market price of formal medicinal gelatin is around 50,000 yuan/ton, while the price of blue alum skin glue is only 15,000-20,000 yuan/ton. Therefore, some unscrupulous manufacturers are driven by profit to use blue alum skin glue (gelatin processed from old leather clothes and shoes) as edible and medicinal gelatin, or use it as an adulterant. The result of such a vicious circle is that it is difficult to guarantee the health of the people.
3. Plant hollow capsules have no risk of gluing reaction
Plant hollow capsules have strong inertness and are not easy to cross-link with aldehyde-containing drugs. The main ingredient of gelatin capsules is collagen, which is prone to cross-linking reactions with amino acids and aldehyde-containing drugs, causing adverse reactions such as prolonged capsule disintegration and reduced dissolution.
4. Low water content of plant hollow capsules
The water content of gelatin hollow capsules is between 12.5-17.5%. Gelatin capsules with high water content tend to easily absorb the water content or be absorbed by the content, making the capsule soft or brittle and affecting the drug itself.
The water content of the hollow plant capsule is controlled between 5-8%, and it is not easy to react with the content above, and it can maintain good physical properties such as toughness for the content of different properties.
5. Plant hollow capsules are easy to store, reducing the storage cost of enterprises
Gelatin hollow capsules have strict requirements on storage conditions and need to be stored and transported at a relatively constant temperature. It is easy to soften and deform at high temperature or high humidity, and brittle and harden at low temperature or low humidity.
Hollow plant capsules have looser conditions. At a temperature of 10-40°C and a humidity of 35-65%, it will not soften, deform, or harden or become brittle. Experiments show that under the condition of 35% humidity, the fragility rate of plant capsules is ≤2%, and when the temperature is 80℃, the capsule change is ≤1%. More relaxed storage requirements can reduce the daily storage costs of enterprises.
6. Plant hollow capsules can isolate the contact with the outside air
The main component of the gelatin hollow capsule is collagen, and the nature of its raw material determines its strong air permeability, making the contents susceptible to adverse effects such as moisture and microorganisms in the air.
The nature of the raw material of the plant hollow capsule determines that it can effectively isolate the contents from the air and avoid adverse effects from the air.
7. Stability of hollow plant capsules
The validity period of gelatin hollow capsules is generally about 18 months, plus the storage time before use, which makes the shelf life of the capsule shorter, which often directly affects the shelf life of the drug. The validity period of hollow capsules is generally 36 months, which significantly increases the validity period of the product.
8. Plant hollow capsules have no preservatives and other residues
In the production of gelatin hollow capsules, preservatives such as methyl parahydroxybenzoate are added to prevent the growth of microorganisms. If the added amount exceeds a certain range, it may eventually affect the excessive arsenic content. At the same time, the gelatin hollow capsules must be sterilized after the production is completed. At present, almost all gelatin capsules are sterilized with ethylene oxide. After ethylene oxide sterilization, there will be residues of chloroethanol in the capsules. The residual ethyl chloride is forbidden to be used abroad.
Our plant capsules do not add any preservatives during the production process. There is no need to sterilize in any way before leaving the factory, and it can fully meet the national standard without any residue. Therefore, the plant capsules produced by our company are healthy green capsules with no preservatives and no residual harmful substances.
9. Plant hollow capsules have lower heavy metals
According to national standards, the heavy metals in animal gelatin hollow capsules cannot exceed 50ppm, and the heavy metals in most qualified gelatin capsules are 40-50ppm. In addition, many unqualified products with heavy metals far exceed the standard.
The heavy metals of the plant capsules produced by our company are far lower than the national standard of 2 parts per million, which shows that the plant capsules are significantly better than animal gelatin capsules.
10. Plant hollow capsules can inhibit the growth of bacteria
The main raw material of animal gelatin hollow capsules is collagen. Generally speaking, collagen is a bacterial culture agent, which helps bacteria to multiply. If it is not handled properly, the number of bacteria will exceed the standard, and it will multiply.
The main raw material of plant hollow capsules is plant fiber, which not only does not multiply bacteria, but also inhibits the growth of bacteria. Tests have proved that the plant hollow capsules can keep the number of microorganisms within the range of national standards when placed in a common environment for a long time.
11. Plant hollow capsules have a looser filling environment, which reduces production costs
When animal gelatin hollow capsules are filled with contents in a fully automatic filling machine, the temperature and humidity requirements of the environment are very high. If the temperature and humidity are too high, the capsule will become soft and deformed; if the temperature and humidity are too low, the capsule will be hardened and brittle; this will greatly affect the pass rate of the capsule. Therefore, the working environment should be kept at about 20-24℃, and the humidity should be kept at 45-55%.
Plant hollow capsules have relatively relaxed requirements for the working environment of the filled contents. The temperature is between 15-30°C and the humidity is between 35-65%, which can maintain a good machine pass rate.
Whether it is the requirements of the working environment or the pass rate of the machine, the use cost can be reduced.
12. Plant hollow capsules are suitable for consumers of different ethnic groups
Animal gelatin hollow capsules use animal bone skin as the main raw material, which has been resisted by Islam, Judaism, and vegetarians. Plant hollow capsules use pure natural plant fiber as the main raw material, suitable for use by any ethnic group.
13. Plant hollow capsule products have high value-added
Although plant hollow capsules have a slightly higher market price, they have more outstanding advantages than animal gelatin hollow capsules. The use of high-end medicines and health care products has significantly improved the grade of products and contributed to the health of consumers. It is especially suitable for products such as anti-biotic and anti-inflammatory drugs, traditional Chinese medicines and high-end health products, making the products have higher value-added and competitive products. force.