Taking medication Note: What medicines do not match grapefruit?


The active ingredient in grapefruit can inhibit the act […]

The active ingredient in grapefruit can inhibit the activity of liver drug enzymes, and many drugs need to be excreted by the metabolism of liver drug enzymes. If you take this kind of medicine and eat grapefruit at the same time, the medicine can not be metabolized and accumulate in the body, which may cause too much effect, affect treatment, and even have adverse reactions.

What are the specific medicines and grapefruits that are not as follows?

Lipid-lowering drugs: If you eat grapefruit during the lipid-lowering drugs such as atorvastatin, lovastatin, and simvastatin, the patient may have muscle pain and rhabdomyolysis, and acute kidney failure may occur in severe cases.

Antihypertensive drugs: Since grapefruit itself also has antihypertensive effect, it can also increase the blood concentration of antihypertensive drugs. When taking antihypertensive drugs such as nifedipine, nimodipine, and verapamil, eat grapefruit or drink grapefruit. Juice, like overdose, causes a sudden drop in blood pressure, which can cause dizziness, palpitation, fatigue, and angina, myocardial infarction, or stroke.
Sedative sleeping pills: Grapefruit will increase the possibility of dizziness and drowsiness caused by drugs such as diazepam (diazepam) and midazolam. Special attention should be paid during the use of drugs by high-altitude workers and drivers.